Real-world biologics response and super-response in the International Severe Asthma Registry cohort
- Creator: Denton, Eve , Hew, Mark , Larenas-Linnemann, Désirée , Murray, Ruth , Celis-Preciado, Carlos Andrés , Al-Lehebi, Riyad , Belhassen, Manon , Bhutani, Mohit , Bosnic-Anticevich, Sinthia Z. , Bourdin, Arnaud , Brusselle, Guy G. , Busby, John , Peters, Matthew J. , Canonica, Giorgio Walter , Heffler, E , Chapman, KR , Charriot, J , Christoff, GC , Chung, LP , Cosio, BG , Côté, A , Costello, RW , Cushen, B , Upham, John W. , Fingleton, J , Fonseca, JA , Gibson, Peter G. , Heaney, LG , Huang, EW-C , Iwanaga, T , Jackson, DJ , Koh, MS , Lehtimäki, L , Máspero, J , Bulathsinhala, Lakmini , Mahboub, B , Menzies-Gow, AN , Mitchell, PD , Papadopoulos, NG , Papaioannou, AI , Perez-de-Llano, L , Perng, D-W , Pfeffer, PE , Popov, TA , Porsbjerg, CM , Tran, Trung N. , Rhee, CK , Roche, N , Sadatsafavi, M , Salvi, S , Schmid, JM , Sheu, C-C , Sirena, C , Torres-Duque, CA , Salameh, L , Patel, PH , Martin, Neil , Ulrik, CS , Wang, E , Wechsler, ME , Price, DB , ISAR LUMINANT Working Group, , Bergeron, Celine , Al-Ahmad, Mona , Altraja, Alan
- Resource Type: journal article
- Date: 2024
Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients
- Creator: Thomas, Dennis , McDonald, Vanessa M. , Gillman, Andrew , Hew, Mark , Hodge, Sandra , James, Alan , Jenkins, Christine , Katelaris, Constance H. , Katsoulotos, Gregory P. , Langton, David , Lee, Joy , Marks, Guy , Stevens, Sean , Peters, Matthew , Radhakrishna, Naghmeh , Reynolds, Paul N. , Rimmer, Janet , Sivakumaran, Pathmanathan , Upham, John W. , Wark, Peter , Yang, Ian A. , Gibson, Peter G. , Harvey, Erin S. , Baraket, Melissa , Bardin, Philip , Bowden, Jeffrey J. , Bowler, Simon , Chien, Jimmy , Chung, Li Ping
- Resource Type: journal article
- Date: 2023
Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both
- Creator: Pfeffer, Paul E. , Ali, Nasloon , Altraja, Alan , Lehtimäki, Lauri , Papadopoulos, Nikolaos G. , Salvi, Sundeep , Costello, Richard W. , Cushen, Breda , Heffler, Enrico , Iwanaga, Takashi , Al-Ahmad, Mona , Larenas-Linnemann, Désirée , Murray, Ruth , Gibson, Peter G. , Fonseca, JA , Al-Lehebi, R , Rhee, CK , Perez-de-Llano, L , Perng Steve, D-W , Mahboub, B , Wang, E , Goh, C , Lyu, J , Ulrik, Charlotte , Newell, A , Alacqua, M , Belevskiy, AS , Bhutani, M , Bjermer, L , Bjornsdottir, U , Bourdin, A , Bulow, AV , Busby, J , Canonica, GW , Tran, Trung N. , Cosio, BG , Dorscheid, DR , Muñoz-Esquerre, M , FitzGerald, JM , Gil, EG , Gibson, PG , Heaney, LG , Hew, M , Hilberg, O , Hoyte, F , Maspero, Jorge , Jackson, DJ , Koh, MS , Ko, H-KB , Lee, JH , Lehmann, S , Chaves Loureiro, C , Lúðvíksdóttir, D , Menzies-Gow, AN , Mitchell, P , Papaioannou, AI , Peters, Matthew , Popov, TA , Porsbjerg, CM , Salameh, L , Sirena, C , Taillé, C , Taube, C , Tohda, Y , Wechsler, ME , Price, DB , Christoff, George C. , Sadatsafavi, Mohsen , Torres-Duque, Carlos A.
- Resource Type: journal article
- Date: 2023
An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype
- Creator: Fricker, Michael , Qin, Ling , Chung, Kian Fan , Gibson, Peter G. , Sánchez-Ovando, Stephany , Simpson, Jodie L. , Baines, Katherine J. , Riveros, Carlos , Scott, Hayley A. , Wood, Lisa G. , Wark, Peter A. B. , Kermani, Nazanin Z.
- Resource Type: journal article
- Date: 2022
Diagnosis and management of allergy and respiratory disorders in sport: an EAACI task force position paper
- Creator: Price, Oliver J. , Walsted, Emil S. , Rukhadze, Maia , Hull, James H. , Bonini, Matteo , Brannan, John D. , Bougault, Valérie , Carlsen, Kai-Håkon , Couto, Mariana , Kippelen, Pascale , Moreira, André , Pite, Helena
- Resource Type: journal article
- Date: 2022
Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders
- Creator: Alemao, Charlotte A. , Budden, Kurtis F. , Mann, Elizabeth R. , El Omar, Emad M. , Belz, Gabrielle T. , Hansbro, Philip M. , Gomez, Henry M. , Rehman, Saima F. , Marshall, Jacqueline E. , Shukla, Shakti D. , Donovan, Chantal , Forster, Samuel C. , Yang, Ian A. , Keely, Simon
- Resource Type: journal article
- Date: 2021
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease
- Creator: Fricker, Michael , McDonald, Vanessa M. , Winter, Natasha A. , Baines, Katherine J. , Wark, Peter A. B. , Simpson, Jodie L. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2021
Sputum macrophage diversity and activation in asthma: Role of severity and inflammatory phenotype
- Creator: Tiotiu, Angelica , Zounemat Kermani, Nazanin , Badi, Yusef , Pavlidis, Stelios , Hansbro, Philip M. , Guo, Yi-Ke , Chung, Kian Fan , Adcock, Ian M.
- Resource Type: journal article
- Date: 2021
Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment
- Creator: Niessen, Natalie M. , Gibson, Peter G. , Peters, Matthew J. , Marks, Guy B. , Baraket, Melissaa , Simpson, Jodie L. , Fricker, Michael , Baines, Katherine J. , Barker, Daniel , Yang, Ian A. , Upham, John W. , Reynolds, Paul N. , Hodge, Sandra , James, Alan L. , Jenkins, Christine
- Resource Type: journal article
- Date: 2021
Epithelial cell dysfunction, a major driver of asthma development
- Creator: Heijink, Irene H. , Kuchibhotla, Virinchi N. S. , Roffel, Mirjam P. , Maes, Tania , Knight, Darryl A. , Sayers, Ian , Nawijn, Martijn C.
- Resource Type: journal article
- Date: 2020
Inhibition of β-catenin/CBP signalling improves airway epithelial barrier function and suppresses CCL20 release
- Creator: Kuchibhotla, Virinchi N. S. , Jonker, Marnix R. , de Bruin, Harold G. , Noordhoek, Jacobien A. , Knight, Darryl A. , Nawijn, Martijn C. , Heijink, Irene H.
- Resource Type: journal article
- Date: 2020
Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis
- Creator: Thyssen, Jacob P. , Ahluwalia, Tarunveer S. , Paternoster, Lavinia , Ballardini, Natalia , Bergström, Anna , Melén, Erik , Chawes, Bo L. , Stokholm, Jakob , Hourihane, Jonathan O'B. , O'Sullivan, Donnchadh M. , Bager, Peter , Melbye, Mads , Bustamante, Mariona , Torrent, Maties , Esplugues, Ana , Duijts, Liesbeth , Hu, Chen , Elbert, Niels J. , Pasmans, Suzanne G. M. A. , Nijsten, Tamar E. C. , Pennell, Craig E. , Wang, Carol A. , von berg, Andrea , Standl, Marie , Schikowski, Tamara , Herberth, Gunda , Heinrich, Joachim , Lee, Young-Ae , Marenholz, Ingo , Lau, Susanne , Curtin, John A. , Simpson, Angela , Custovic, Adnan , Holt, Patrick G. , Bisgaard, Hans , Bønnelykke, Klaus
- Resource Type: journal article
- Date: 2020
Sputum basophils are increased in eosinophilic asthma compared with non-eosinophilic asthma phenotypes
- Creator: Brooks, C. R. , van Dalen, C. J. , Hermans, I. F. , Gibson, P. G. , Simpson, J. L. , Douwes, J.
- Resource Type: journal article
- Date: 2017
Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice
- Creator: Nair, P. M. , Starkey, M. R. , Haw, T. J. , Liu, G. , Horvat, J. C. , Morris, J. C. , Verrills, N. M. , Clark, A. R. , Ammit, A. J. , Hansbro, P. M.
- Resource Type: journal article
- Date: 2017
Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype
- Creator: Scott, H. A. , Gibson, P. G. , Garg, M. L. , Upham, J. W. , Wood, L. G.
- Resource Type: journal article
- Date: 2016